75% of those affected Guillain–Barré syndrome ( GBS) is a rapidonset muscle weakness caused by the immune system damaging the peripheral nervous system Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body GuillainBarré syndrome (GBS) can be described as a collection of clinical syndromes that manifests as an acute inflammatory polyradiculoneuropathy with resultant weakness and diminished reflexes With poliomyelitis under control in developed countries, GBS is now the most important cause of acute flaccid paralysisRopper, AH The GuillainBarre Syndrome PowerPoint PPT presentation free to view
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Guillain barre syndrome pathophysiology ppt-The exact pathogenesis of Guillain Barre syndrome is not completely understood but in 2/3 of cases there is a history of an infectious disease in the past month The most common pathogens responsible for these antecedent infections are Campylobacter jejuni Cytomegalo virus Hemophilus influenzaeGuillainBarre Syndrome Plasmapheresis and acute GuillainBarre syndrome The GuillainBarre Syndrome Study Group Neurology 1984;



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GuillainBarré syndrome is a clinically diagnosed disorder, but nerve conduction studies (NCS) can help to support the diagnosis, to discriminate between axonal and demyelinating subtypes, and could relate to prognosis Nerve conduction abnormalities are most pronounced 2 weeks after start of weakness 58GuillainBarre' GuillainBarre' Syndrome Postinfectious polyneuropathy;M Ãirst described by Landry in 1859, occurs throughout the world, affects children adults of both sexes, but is more prevalent on men, and all age groups equally, and occurs in all seasons of the year m Commonly caused by viral agents À À ¦ ½ ½ m An increased incidence of GuillainBarré syndrome occurred after influenza vaccination in therefore, the syndrome continues
GuillainBarré Syndrome GuillainBarré syndrome, also called acute inflammatory demyelinating polyneuropathy (AIDP), affects one to two new persons per 00,000 population each year It can strike anyone without warning regardless of gender, age or ethnic background About 50 percent of patients initially develop abnormal sensationsAbout Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How works Test new features Press Copyright Contact us Creators In GuillainBarré syndrome, the body's immune system attacks part of the peripheral nervous system The syndrome can affect the nerves that control muscle movement as well as those that transmit feelings of pain, temperature and touch This can result in muscle weakness and loss of sensation in the legs and/or arms
Classical GuillianBarré Syndrome (GBS) • As described by Landry in 2 1 Landry O Gazette Hebdomadiare de Médecine et de Chirurgie 1859;6472–74 et 1859;6486–GuillainBarre syndrome (GBS) is a complicated degenerative neurological disorder which can be acute or chronic in nature It is an acquired condition which is characterized by progressive, symmetrical, proximal and distal tingling and weakness Muscle stretch reflexes are decreased to absent and loss of sensation is common GuillainBarré syndrome (GBS), or acute inflammatory demyelinating polyradiculoneuropathy (AIDP), describes a heterogeneous condition with a number of redundant variants The classic presentation is characterized by an acute monophasic, nonfebrile, postinfectious illness manifesting as ascending weakness and areflexia



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GuillainBarre syndrome is a rare but serious autoimmune disorder that affects the peripheral nervous system The peripheral nervous system is the portion of the nervous system that is outside the brain and spinal cord Autoimmune means the patient's immune system begins to attack healthy tissue, which in this case are nerve cells which GUILLAIN BARRE SYNDROME IS AN ACUTE INFECTIOUS DEMYELINATING POLYRADICULONEUROPATHYIMP IN DIFFERENTIAL DIAGNOSISGuillain Barre Syndrome(gheeyanbar syndrome) also known as landry's palsy is a classic lower motor neuron disorder It is a reactive self limited autoimmune disease in which the body's immune system attacks part of the peripheral nervous system[1]



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Guillain–Barré syndrome also known as Landry's paralysis is an autoimmune disorder in which the peripheral nervous system of a person is attacked by the body's immune system resulting in rapidonset muscle weakness and degeneration, the disorder can be lifethreatening with the development of weakness in the breathing muscles and requiring mechanical ventilation,Http//wwwmedicaldumpcom Please visit the site for FREE medical PowerPoints, medical PowerPoint templates, medical pdfs related to all specialties includAscending polyneuropathic paralysis An acute, rapidly progressing and potentially fatal form of polyneuritis GuillainBarre' Syndrome Affects the peripheral nervous system GuillainBarre' Tcell sensitization occurs which causes loss of myelin which disrupts nerve impulses Loss of myelin,



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GuillainBarré syndrome Hugh J Willison, Bart C Jacobs, Pieter A van Doorn GuillainBarré syndrome is the most common and most severe acute paralytic neuropathy, with about 100 000 people developing the disorder every year worldwide Under the umbrella term of GuillainBarré syndrome are severalGuillainBarreSyndrome is the main causes of the paralysis in neuromuscles GBS mainly have subtypes Acute motor axonal neuropathy (AMAN) Another subtypes is acute inflammatory demyelinating polyneuropathy (AIDP) The most commonGuillainBarre Syndrome GuillainBarre Syndrome Nerve Roots (GBS) by n8dgr8 Etiology and Pathophysiology Cause of this disorder is unknown Believe to be a cellmediated immunologic reaction directed at peripheral nerves The PowerPoint PPT presentation "Le Syndrome GuillainBarr" is the property of its rightful owner



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GuillainBarre´ Syndrome Ted M Burns, MD1 ABSTRACT GuillainBarre´ syndrome (GBS) is an acuteonset, monophasic, immunemediated polyneuropathy that often follows an antecedent infection The diagnosis relies heavily on the clinical impression obtained from the history and examination, although cerebroAbstract GuillainBarre Syndrome (GBS) is a disease which causes damage in the peripheral nervous system GuillainBarre Syndrome refers to a group of disorders, including several variants such as acute inflammatory demyelinating polyradiculoneuropathy, acute motor axonal neuropathy, acute motorsensory axonal neuropathy, as well as, Miller Fischer SyndromePlasmapheresis and acute GuillainBarre syndrome The GuillainBarre Syndrome Study Group Neurology 1984;



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GuillainBarré syndrome is one of several disorders involving weakness due to peripheral nerve damage caused by the person's immune system While GBS comes on rapidly over days to weeks, and the person usually recovers, other disorders develop slowly andGuillainBarre Syndrome Nerve Roots (acute polyradiculopathies) GuillainBarre Syndrome Lyme disease Sarcoidosis HIV Other viruses (CMV, VZV, West Nile) Cauda Equina – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShowcom id 6e54ffOWU4OHistorical Note JeanBaptiste Octave Landry in 1859 first described a case of distal sensory "formications" and ascending weakness after a prodromal fever, malaise and pain who progressed to paralysis over 3 weeks and died from respiratory failure in addition to another 4 casesSixty years later, Georges Guillain, JeanAlexandre Barré, and Andre Strohl reported two cases with



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GuillainBarré syndrome consists of a group of neuropathic conditions characterized by pro gressive weakness and diminished or absent myotatic reflexes The Most people with the condition must be hospitalized to receive treatment The exact cause of GuillainBarre syndrome is unknown But twothirds of patients report symptoms of an infection in the six weeks preceding These include respiratory or a Pediatric GuillainBarré syndrome Prof Dr Saad S Al Ani 48 Spinal cord lesions may be considered in the differential diagnosis • Transverse myelitis • Vascular malformations • Epidural abscess • Cord infarctions • Tumors • Cord compression • Enteroviral infections of the anterior horn cells • Lumbosacral disk syndromes • Poliomyelitis • Trauma •



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GuillainBarre syndrome (GBS) is a rare but serious postinfectious immunemediated neuropathy It results from the autoimmune destruction of nerves in the peripheral nervous system causing symptoms such as numbness, tingling, and weakness that can progress to Nature Reviews Neurology Guillain–Barré syndrome (GBS) is a postinfectious disease characterized by rapidly progressive, symmetrical weakness ofRopper, AH The GuillainBarre Syndrome – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShowcom id 45ba53MWZlY



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And which presents as acute generalized weaknessDOI /NEJMra The Guillain–Barré syndrome is the most frequent cause ofGUILLAINBARRE SYNDROME GUILLAINBARRE SYNDROME RAJAT PAREEK, MD INTRODUCTION Postinfectious polyneuropathy Mainly Motor Nerves, occ Sensory and Autonomic nervous system – PowerPoint PPT presentation PowerShowcom is a leading presentation/slideshow sharing website



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GUILLAINBARRE SYNDROME Timothy Dycalle P Manos, RN SO GUILLAINBARRE (GHEEYABUHRAY) It is an acute, autoimmune, rapidly progressive, potentially fatal syndrome It is an autoimmune disease bodys immune system begins to trigger demyelination of the peripheral nerve a problem with your nervous system GuillainBarre syndrome can be difficult to diagnose in its earliest stages Its signs and symptoms are similar to those of other neurological disorders and may vary from person to person Your doctor is likely to start with a medical history and thorough physical examination GuillainBarre' Syndrome Affects the peripheral nervous system 6 PATHOGENESIS Peripheral nerve demyelination in GuillainBarré syndrome is believed to be immunologically mediated Humoral factors and cellmediated immune phenomena have been implicated in the damage of myelin and/or the myelinproducing Schwann cells



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Causes GuillainBarré syndrome is thought to be caused by a problem with the immune system, the body's natural defence against illness and infection Normally the immune system attacks any germs that get into the body But in people with GuillainBarré syndrome, something goes wrong and it mistakenly attacks the nerves Guillain barre syndrome (gbs) 1 GuillainBarre Syndrome (GBS( Dr Mohamed Abunada Pediatric Neurology Department Dr Al rantisi specialized children Hospital 2 Outline Definition Epidemiology Etiology Pathogenesis & Pathology Clinical features Investigations Diagnosis Differential diagnosis Treatment Prognosis 3The typical patient with GBS, which in most cases will manifest as acute inflammatory demyelinating polyradiculoneuropathy (AIDP), presents 24 weeks following a relatively benign respiratory or



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Yuki N, Susuki K, Koga M, et al Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes GuillainBarre syndrome Proc Natl Acad Sci U S A 04; N Engl J Med 12;Guillain Barré syndrome – pronounced GEEYan BuhRAY – is a rare condition in which your immune system attacks your nerves Although several types of the condition occur, in the United States, Guillain Barré syndrome (GBS) most often affects the peripheral nerves that connect your brain and spinal cord to the rest of your body



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DEFINITION Guillain–Barré syndrome (GBS) 0r Landry's paralysis It is a disorder in which the body's immune system attack part of the peripheral nervous system It is an acute, progressive, autoimmune, inflammatory demyelination of polyneuropathy 0f the peripheral sensory and motor nerves and nerve roots 4Yuki N, Yamada M, Koga M, et al Animal model of axonal GuillainBarré syndrome induced by sensitization with GM1 ganglioside Introduction Guillain–Barré syndrome (GBS) is now a wellknown disorder of the peripheral nervous system (PNS) Nevertheless, for approximately nine decades from the first report of GBS, the disease was considered to have a spinal cord origin 1 Since the first clinical report, the accumulation of detailed clinicopathological data has shown that the classical form of



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PPT GuillainBarre Syndrome PowerPoint presentation GuillainBarré syndrome (GBS), with an annual incidence of 12 per 100,000, is the most common cause of neuromuscular paralysis in the western worldGuillainBarré syndrome consists of a group of neuropathic conditions characterized by progressive weakness and diminished or absent myotatic reflexes The estimated annual incidence in the United States is 165 to 179 per 100,000 persons GuillainBarré syndrome is believed to result from an aberrThis discussion of GuillainBarre includes etiology,pathophysiology,symptoms/features,diagnosis, and treatment



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